Drew and Paul head to the scene of a multi-car collision. Paul takes a chance on a daring rescue and sustains injuries that could jeopardize his dreams to be a surgeon. Back at the ER, the newly-anointed Dr. Ragosa along with Jordan, Scott, Krista and Kenny, manage the deluge of incoming victims. They soon discover the disturbing cause of the accident. Meanwhile, TC and Topher head into a war zone to treat an old friend who is in desperate need of sophisticated medical attention. As the danger grows more intense, both TC and Topher reflect on their decision to risk their lives.