One night in 2019, politician Vivienne Rook causes a scandal on live TV. At the same time, the Lyons family comes together as Rosie gives birth to a son. Brothers Stephen and Daniel gather at her bedside with grandmother Muriel, all wondering what life will be like for little Lincoln. Five years in the future, in the London of 2024, Stephen and Celeste worry about their daughter, Bethany, who declares herself a transhuman. Back in Manchester, Daniel is now married to Ralph but is falling for a Ukrainian refugee, Viktor. When the Lyons gather for Muriel's birthday, they're interrupted by a call from their missing sister, Edith. She brings extraordinary news, and life for the Lyons is about to change forever.