Condemned man Howard Epps is scheduled to be executed by lethal injection in 32 hours for the murder of 17-year-old April Wright. Epps' attorney, Amy Morton, makes a last-minute appeal to Booth, the man who arrested Epps, to re-examine the case. Booth believes Epps is guilty, but acknowledges that the case had a few loose ends. He asks Dr. Temperance Brennan and her team of squints to review the evidence and confirm Epps' guilt. But when Brennan finds forensic anomalies in the case, and Booth turns up evidence that another man was with April Wright the night she died, they must race against the clock to stay the execution.