Imagine having two twin brainiac sisters who are 13 years old and can bring up out-of-this-world experiments. Well lucky for "Johnny Test" and his super talking dog, Dukey. They can. Super-powers, gadgets that can rewind a person or turning things into gold... for Johnny the possibilities are endless. But whenever there is trouble, Johnny has to go back home before 5 P.M. for meatloaf.