Main Characters
David Letterman
4262 main appearances
Paul Shaffer
4262 main appearances
Alan Kalter
3822 main appearances
Recurring Guest Characters
Announcer
195 guest appearances
Regis Philbin
116 guest appearances
Tom Brokaw
21 guest appearances
Bill Cosby
19 guest appearances
Tom Arnold
18 guest appearances
Jack Hanna
18 guest appearances
Norm Macdonald
18 guest appearances
David Brenner
17 guest appearances
Charles Grodin
17 guest appearances
Jeff Goldblum
15 guest appearances
Jon Stewart
15 guest appearances
Richard Simmons
15 guest appearances
Sarah Jessica Parker
14 guest appearances
Marv Albert
14 guest appearances
Fran Drescher
13 guest appearances
Nathan Lane
13 guest appearances
Barbara Walters
12 guest appearances
Michael J. Fox
12 guest appearances
Bruce Willis
12 guest appearances