Guest Stars Camilla Luddington as Dr. Jo Wilson Tessa Ferrer as Dr. Leah Murphy Justin Bruening as Matthew Taylor Kyle Silverstein as Ethan Dawson Michael Buie as Paul Dawson Charles Michael Davis as Dr. Jason Myers Enid Graham as Rachel Dawson Jennifer Bassey as Nancy Dawson Sarah Lilly as Joyce Basche Tom Costello as Seth Lepik Abbie Cobb as Francis "Frankie" Keller Idara Victor as Amelie Ward Anthony Montgomery as Chris Ward Steven M. Gagnon as Mr. Lepik Mike Hagerty as Al Keller Thom Barry as CDC Investigator Katy Kurtzman as Deedee Keller Anton Narinskiy as Gunnar Andrew Manning as Tony Keller Elisabeth Noone as Bess Lepik Robin DeMarco as Jane Keller Sam Fuller as Cash Keller