In order to "save" Stewie from autism, Peter and Lois decide not to vaccinate him and then proceed to convince the rest of Quahog to follow suit. Stewie runs away to save himself from diseases until Sean Penn (guest-voicing as himself) swoops in to save the day and brings vaccines to the whole town.
Guest Cast
Patrick Warburton
voices Joe Swanson
Fred Tatasciore
voices John Goodman
Cast Appearances
Seth MacFarlane
voices Peter Griffin
Seth MacFarlane
voices Stewie Griffin
Seth MacFarlane
voices Brian Griffin
Alex Borstein
voices Lois Griffin
Seth Green
voices Chris Griffin
Mila Kunis
voices Meg Griffin
Seth MacFarlane
voices Tom TuckerEpisode Discussion
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