Leslie Winkle, also a PhD, works together in the same lab as Leonard. They are enemies as they always have conflicting theories.
Appearances
The Big Bang Theory
Main cast, played by Sara Gilbert
- Episode 2x02: The Codpiece Topology (Sep 29, 2008)
- Episode 2x03: The Barbarian Sublimation (Oct 6, 2008)
- Episode 2x06: The Cooper-Nowitzki Theorem (Nov 3, 2008)
- Episode 2x16: The Cushion Saturation (Mar 2, 2009)
Guest cast, played by Sara Gilbert
- Episode 1x03: The Fuzzy Boots Corollary (Oct 8, 2007)
- Episode 1x05: The Hamburger Postulate (Oct 22, 2007)
- Episode 1x13: The Bat Jar Conjecture (Apr 21, 2008)
- Episode 3x23: The Lunar Excitation (May 24, 2010)
- Episode 9x17: The Celebration Experimentation (Feb 25, 2016)