Guy Fieri brings in chefs from the four corners of the U.S. to see which region has the tastiest food. He starts off the competition by asking the chefs to cook their best regional sandwich, but on a budget. Then they have to make seafood dishes using ingredients from around the market. Finally, Guy's food wheel decides where the remaining two chefs get to shop for their regional comfort food dishes. In the end, only one chef will prove that their region reigns supreme and go on a shopping spree worth up to $20,000.