The ER faces a staff shortage when several employees are sent home with food poisoning, including Weaver. Mark and Elizabeth's marriage is in crisis following Ella's hospital admission. Adding to his woes, Mark fears his brain tumor may have returned. Eleanor Carter nearly abandons young Mickey after realizing how bad his condition is. Abby pays the price to protect Joyce from her violent husband, Brian, when she is punched by him. Luka later tracks down Brian and threatens to kill him.