William Compton dies of the "sweating sickness" at Compton Wynates, his house in Warwickshire. As King Henry VIII receives positive news of his war against Emperor Charles, the sickness spreads like a wildfire. Henry flees the palace and London, and starts having doubts about the future and his ability to rule the country. Both Anne Boleyn and Cardinal Wolsey are stricken with the disease, but recover. Wolsey sends agents to the exiled Pope asking for him to make a favorable decision on Henry's 'Great Matter' but Clement instead sends his legate, Cardinal Campeggio, to make a final decision in England.