Medical Center followed surgeons working in an otherwise unnamed university hospital in Los Angeles. The show focused both on the lives of the doctors as well as the patients showcased each week. At the core of the series was the tension between youth and experience, as seen between Drs. Lochner and Gannon. Besides his work as a surgeon, Gannon, because of his age, also worked as the head of the Student Health Department at the University. Helping the doctors was the very efficient Nurse Eve Wilcox.