The series is about the two 25-year-old twins, happiness and Thomas, who have lost both their parents. One tries to find happiness through the career, the other through love. Thomas has for several years been treated for depression, while Happiness, however, has focused on his career. The start of the series, she seeks job in the communications department at the pharmaceutical giant SanaFortis, where she focuses on a meteoric career. In addition, we meet in the course of the series a wide range of other personalities who undergo astonishing changes when their perception of happiness in turn challenged. Happiness is a comedy about ambition and repressed instincts, the unclear border between dream and reality and the dream of happiness and well-ordered life, where everything can be planned - except for the case.