Ben and Rook follow Maltruant through the time stream. Ben has an adventure with George Washington, in 1773, fighting Maltruant and Vilgax. After defeating Vilgax, Ben and Rook chase Maltruant in the time stream to the beginning of time itself onto the starship of the Contemelia (the creators of the Annihilaarg) where Maltruant attempts to create a universe of his own using his own Anihilaarg. In a climactic battle, at the beginning of time Ben nearly dies trying to stop Maltruant from building his own universe but then it is revealed that the Omnitrix has a fail-safe to prevent its keeper from dying.
Using the combined power of all of the Omnitrix aliens', Ben absorbs the Dwarf Star-powered Anihilaarg and uses its immensely strong, destructive power to defeat Maltruant, trapping him in a time loop that will result in him reliving the same events eternally. The Contemelia then reveal the origins of Skurd, declaring the Slimebiote to be the most vital extraterrestrial being in all of creation (to Skurd's shock). As Skurd departs with his ancestors to help develop the New World, Ben and Rook look on in awe. A new dawn rises as Ben creates a universe of his own. Back on Earth, feeling bored after the incredible sight they witnessed, Ben decides to go on a road trip across the recreated universe with Rook, Gwen and Kevin.