Special Guest Stars Rhea Perlman as Annette Castellano Guest Stars Chris Messina as Dr. Daniel "Danny" Castellano Rebecca Rittenhouse as Dr. Anna Ziev Jenny O'Hara as Dot Tipper Newton as Karen Simmons Max Minghella as Richie Castellano Richard Gant as Melville Fuller Rob McElhenney as Lou Tookers Yassir Lester as David Co Starring Chris Schleicher as Nurse Chris James O'Halloran as Hot Man #2 Nick Baga as Hot Man #1 Matt Warburton as Skeevy-Looking Doctor Houston Rhines as Last Guy Christopher Chen as Dr. Clarence Choi Nina Millin as Sourpuss Braxton Beckham as Doogie Howser Ronin Lee as Hot Man #3 Jed Henry as Hot Man #4
