FA Cup holders Manchester City travel across the Pennines to face Championship side Sheffield Wednesday, who are vying to reach the quarter-finals for the first time since 1997.
Garry Monk's Owls have already overcome Premier League Brighton en route to this stage, but they've gone 11 games without a win against Manchester City, who are visiting Hillsborough for the first time since a 1-1 FA Cup draw 13 years ago.
This is a third successive cup game for City, having faced Real Madrid in the Champions League and then Aston Villa in the Carabao Cup final just three days before this tie.
The draw for the quarter-finals will take place after the conclusion of this game.
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