Guest Stars Neil Stuke as Senior Civil Servant, DoH Ophelia Lovibond as Carrie Symonds Andrew Buchan as Matt Hancock Aimée Kelly as Alison Simon Paisley Day as Dominic Cummings Jimmy Livingstone as Chris Whitty James Corrigan as Isaac Levido Philip Buck as Martin Reynolds Derek Barr as Lee Cain Shri Patel as Rishi Sunak Tom Andrews as Tom Armstrong Ben Lloyd-Hughes as Ben Gascoigne Justin Edwards as Mark Sedwill Michael Colgan as Gabriel Milland Simon Lowe as James Slack Joe Bannister as Jack Doyle Lee Comley as Ben Wasim Zakir as Amir Hamdi Salima Saxton as Teena Heather Peace as Mary Wakefield Olivier Huband as Jamie Greta Bellamacina as Cleo Watson Isabella Javor as Lara Albin Calderon as Manny Hiten Patel as Downing Street Security Guard Simon Treves as NHS Medical Director Orson Berthier Ronald as Cedd Daniel Marot as Milo Sam Dutton as DoH Official Andrew Ehrensperger as Theo Simon Kunz as Andrew Mills Patrick Grant as Cookson and Clegg Angela Wynter as Sarah Boateng Mark Lewis as Steven Green Tim Berrington as John Newton Georgia Bowers as Landermeads Carer Bob Hopkinson as Resident Edward Ofosu-Osei as Tony Boateng Olivia-Rose Burton as Cassia Caroline Bowers as Landermeads Carer Hannah Figgens as Landermeads Carer Rizwan Khan as Downing Street Doctor Lindsey Riding as Nurse Jane Bertish as Claire Green Keshini Misha as Rubaya Ajay Chabra as Jin Sahota Carly Bawden as Jo Green Jaeceena Anderson as Asale Child Michelle Asante as Grace Edward Cole as Durham Police Officer Angela Carruthers as Factory Manager Gilly Daniels as Resident Darryl Mundoma as Asale Child James McNicholas as Deloitte Advisor Jessica Hof as DoH Official Timothy Edward Bartholomew as Robert Keshav Shree as Dentist Gbolahan Obisesan as Frank Sandra Voe as Morag Ross Hatt as Norwich Doctor Freddie Meredith as Adam Green
