Lonnie Ali, a native of Louisville, Kentucky, completed her BA degree at Vanderbilt University in Nashville in 1978. After graduation, Lonnie began her business career with Kraft Foods, Inc. She continued her studies at UCLA's Graduate School of Management and received an
MBA in 1986.
After her marriage to Muhammad Ali in November 1986, she assumed responsibility and management of his business affairs. In 1992, she formally incorporated Greatest of All Time, Inc. (GOAT Inc.) to centralize and license her husband's intellectual properties for commercial purposes. She served as Vice President and Treasurer of GOAT, Inc. until the sale of the company in 2006. During her tenure, Lonnie managed the company's daily operations and accompanied Muhammad on business trips and humanitarian initiatives, domestically and around the world. After the sale of GOAT, Lonnie was asked to serve on the management board of the newly formed Muhammad Ali Enterprises.