Main Characters
David Letterman
4262 main appearances
Paul Shaffer
4262 main appearances
Alan Kalter
3822 main appearances
Recurring Guest Characters
Mykelti Williamson
1 guest appearances
Steve Buscemi
1 guest appearances
Alex Trebek
1 guest appearances
Neneh Cherry
1 guest appearances
Youssou N'Dour
1 guest appearances
Edie Brickell
1 guest appearances
Harry Anderson
1 guest appearances
Charlie Musselwhite
1 guest appearances
Waylon Jennings
1 guest appearances
John Irving
1 guest appearances
Freedy Johnston
1 guest appearances
John Ridley
1 guest appearances
Marshall Crenshaw
1 guest appearances
Dudley Moore
1 guest appearances
Mark Strausman
1 guest appearances
Margaret Cho
1 guest appearances
Cynthia McFadden
1 guest appearances
Mickey Rourke
1 guest appearances
Sammy Kershaw
1 guest appearances