Paul O'Grady's Little Heroes - Episode Guide

In this episode, Paul meets 13-year-old Mackenzie, who was born with microtia, a condition that meant his left ear was underdeveloped. He also meets brother and sister Emily and Luke, who were both born with cystic fibrosis, and gutsy nine-year-old Lara who has a blood disease that has affected her since she was a baby.

In the second episode of series, Paul joins eight-year-old patient Lily for a scoot around the hospital corridors. Lily was rushed to GOSH three months earlier with severe pain in her thigh. After a week of tests she was diagnosed with a rare and aggressive form of leukaemia.

In the third episode of series, Paul meets 11-year-old patient Fazeel, who suffers from a rare condition known as EB, which effects just 5000 people in the UK and currently has no cure. Fazeel's condition means he has delicate, painful skin and also needs regular eye checks to look for damage or blistering inside the eye.

Paul meets 13-year-old, dog-loving Amelie, who's been coming to GOSH since she was a baby with a very rare case of juvenile idiopathic arthritis. Paul also gets to meet another little girl that has lived at GOSH since she was 11 months-old, three-year-old Esme, who has a complex heart condition. Lastly, Paul meets eight-month-old little charmer Alexander, who was born profoundly deaf. He's going to have surgery which could mean Alexander will finally be able to hear!

In episode 5, Paul first meets three-year-old Angel who is a regular visitor to Eagle Ward, the hospital's kidney centre. Effervescent Angel has been visiting GOSH three times a week for two and a half years as she needs dialysis while she waits for a new kidney, and her infectious personality has made her a much-loved patient. Paul is soon smitten by her positive character, so much so he readily accepts her invitation to her upcoming birthday party on the ward – but when the big day arrives, can he help make it a celebration Angel will never forget?

In the final episode of the series, Paul meets nine-year-old Ocean who was in perfect health until she woke up one morning with a headache and a mysterious swelling on her forehead. Following tests, Ocean was diagnosed with Pott's Puffy Tumour, a very rare life-threatening bone infection. Ocean bravely says, "I wasn't scared or worried, I was just wondering what it was."

In the first episode of series, Paul meets five-year-old Daniel who has been in the hospital for a month unable to walk properly after banging his knee whilst playing at home. Just after his accident, Daniel began struggling to walk and he was diagnosed with a rare type of arthritis.

In the second episode Paul meets 13-year-old Lola who has been in hospital for four weeks after being diagnosed with Juvenile Dermatomyositis which has caused inflammation of her muscles and skin. When Paul meets Lola her muscles are so weak and she can't walk, but her mum explains that just six weeks earlier she had been fine. The condition affects one in a million people and Lola needs physiotherapy to help her. Paul is there when Lola tried to take some steps for the first time in two months.

Also in the programme, Paul meets ten-year-old Oscar who has Tourette's. Oscar mostly has motor ticks, which means he sniffs and coughs. He explains that it's a human glitch which causes him to have involuntary movements. But he tells Paul that after developing Tourette's he became too anxious to leave the house.

Paul hears the story of six-year-old Noah, who was born with a genetic disorder that affects the body's organs and has been referred to Great Ormond Street for the removal of his kidney, which stopped working a long time ago. The presenter also meets a couple of two-year-olds - Lucas who has a detached retina and needs laser surgery on his eye and Taylor-Rose who has accidentally swallowed a watch battery.

In episode four Paul meets five-year-old Cora who has Cerebral Palsy. Thirty thousand children in the UK have the condition which affects coordination and muscle control. Cora's mum Poonam explains that Cora has a stiffness in the right side of her body which is causing her to limp and struggle with normal movements.

Cora is at GOSH to take part in ground breaking research which uses Botox to relax the over-active muscles. Paul goes with Cora to the sensory room to try to distract and relax her whilst she has the injections. And the programme follows Cora after the injections to see if they have worked.

Also in episode four, Paul reveals that he's developed a soft-spot for babies. GOSH treats 6000 babies every year and Paul goes to meet three-month-old Oliver who was born with a cleft lip. Paul is with Oliver as he enters theatre to have his cleft lip repaired.

In episode five Paul meets 13-year-old Noah who is at GOSH to have an operation on his skull because part of it is pressing on his spinal cord. Noah's mum Georgina tells the programme that Noah is anxious about the surgery after undergoing emergency surgery on his brain when he was just six.

Paul meets charming four-year-old Lucy, who has travelled down from Glasgow for the latest check-up to monitor her pulmonary hypertension - a high blood pressure condition that affects the lungs. He also meets remarkable 13-year-old Connor, who is on the isolation ward as he prepares for a bone marrow transplant to help treat leukaemia. As Connor needs to live in a totally sterile environment to protect his weakened immune system, Paul can only speak to him through a window - but that doesn't stop him finding a number of fun and interesting ways to keep Connor occupied during his recovery.