Most Extreme Humans follows people from around the globe living with the world's rarest and most remarkable physical conditions. From a Filipino man whose hands have grown so large he wears wristwatches as rings, to Brazil, where the world's smallest married couple have a combined height under six feet, to a 19-year-old in India living with the ultra-rare condition known as "werewolf syndrome." This series examines what everyday life looks like when the world is not built with your body in mind.
Show Info
Schedule: Wednesdays at 21:00
(60 min)
Status: Running
Show Type:
Reality
Genres:
Medical
Episodes ordered: 10 episodes
(waiting for more votes)
Next Episode
Skin in the Game
Episode 1x07; Jul 22, 2026
Mahfuza and Nelly are living with Harlequin ichthyosis, one of the world's rarest and most severe skin conditions. Mahfuza prepares for her first boxing match. Nelly fully supports her friend but worries that the high risks may outweigh the rewards.
Previous Episodes
| Episode Name | Airdate | Trailer |
|---|---|---|
| 1x06: Hair Today, Gone Tomorrow? | Jul 15, 2026 | |
| 1x05: Face to Face | Jul 8, 2026 | |
| 1x04: Peaks and Valleys | Jul 1, 2026 |





