Most Extreme Humans follows people from around the globe living with the world's rarest and most remarkable physical conditions. From a Filipino man whose hands have grown so large he wears wristwatches as rings, to Brazil, where the world's smallest married couple have a combined height under six feet, to a 19-year-old in India living with the ultra-rare condition known as "werewolf syndrome." This series examines what everyday life looks like when the world is not built with your body in mind.
Show Info
Schedule: Wednesdays at 21:00
(60 min)
Status: Running
Show Type:
Reality
Genres:
Medical
Episodes ordered: 10 episodes
(waiting for more votes)
Next Episode
Face to Face
Episode 1x05; Jul 8, 2026
Milagros lives with tumors so heavy that her face droops down to her torso; after hiding away, a health scare is forcing her out into the world; twenty-one-year old Lizzie is preparing to live independently even after tumors have grown over her eyes.
Previous Episodes
| Episode Name | Airdate | Trailer |
|---|---|---|
| 1x04: Peaks and Valleys | Jul 1, 2026 | |
| 1x03: Upside Down with a Twist | Jun 24, 2026 | |
| 1x02: Ugliest Man | Jun 17, 2026 |




