Guest Stars Mare Winningham as Diane Mallum Will Chase as Michael Friedman Ray McKinnon as Jerry Mallum Phillipa Soo as Amber Collins Ian Unterman as Jonathan Sackler Brendan Patrick Connor as Howard Udell Raúl Esparza as Paul Mendelson Andrea Frankle as Beth Sackler Lawrence Arancio as Raymond Sackler Jaime Ray Newman as Kathe Sackler Jake McDorman as John Brownlee Cleopatra Coleman as Grace Pell Winsome Brown as Theresa Sackler Walter Bobbie as Mortimer Sackler Alan Campbell as Dr. Paul Goldenheim Linda Powell as Karen Moles Rebecca Wisocky as Cynthia McCormick Kenneth Tigar as Arthur Sackler Adam Grupper as Purdue Lawyer Meagen Fay as Sister Beth Davies Amy Rutberg as Alice Fisher Brian Keane as Curtis Wright Co Starring Deadra Moore as Karen Johnson R. Keith Harris as Martin Willis Andres Erickson as Mortimer D.A. Sackler Morgan Brown as Gregg Wood Alayna Hester as Elizabeth Ann McClung Deja Dee as Stephanie Mountcastle Paden Fallis as Louis Melton Vince Pisani as David Gauvin Anthony Reynolds as Sheriff Serena Ebhardt as Sue Ella Kobak Van Zee Travis Smith as Eric Miller Ray Dooley as Dr. Art Van Zee Michael Silberblatt as Drug User at Bridge Kenny Alfonso as Medical Board Administrator Cory Scott Allen as Tim Taylor Simmons as Drug User at House Mark Cabus as Senator Kefauver Nicole Burgess as New Sales Rep Jon Hayden as Senator Chris Dodd Mary Kraft as Dr. Deborah Leiderman Christie Duke as Receptionist
