Main Characters
David Letterman
4262 main appearances
Paul Shaffer
4262 main appearances
Alan Kalter
3822 main appearances
Recurring Guest Characters
William H. Macy
2 guest appearances
Jamiroquai
2 guest appearances
Missy Elliot
2 guest appearances
Sarah O'Hare
2 guest appearances
Angelo Massagli
2 guest appearances
Terrell D. Davis
2 guest appearances
Pam Grier
2 guest appearances
Matt Damon
2 guest appearances
Jim Breuer
2 guest appearances
Jonny Moseley
2 guest appearances
Marilyn Manson
2 guest appearances
Natalie Imbruglia
2 guest appearances
Hatty Jones
2 guest appearances
Steve Earle
2 guest appearances
Jerry Springer
2 guest appearances
Billy Bragg
2 guest appearances
Lucinda Williams
2 guest appearances
French Stewart
2 guest appearances
Bobby Rahal
2 guest appearances