Main Characters
David Letterman
4262 main appearances
Paul Shaffer
4262 main appearances
Alan Kalter
3822 main appearances
Recurring Guest Characters
Jonathan Silverman
2 guest appearances
Gena Lee Nolin
2 guest appearances
Cher
2 guest appearances
Ving Rhames
2 guest appearances
Brent Spiner
2 guest appearances
Margaret Colin
2 guest appearances
Lea Thompson
2 guest appearances
Rhea Perlman
2 guest appearances
Reggie McFadden
2 guest appearances
George Jones
2 guest appearances
Susan Molinari
2 guest appearances
Natasha Henstridge
2 guest appearances
Goldie Hawn
2 guest appearances
Julie Andrews
2 guest appearances
Bryan White
2 guest appearances
Chris Pine
2 guest appearances
Eriq La Salle
2 guest appearances
Marc Maron
2 guest appearances
James Woods
2 guest appearances