Guest Stars Frances Turner as Barb Howard Sarita Choudhury as Kate Williams / Lee Moldaver Michael Esper as Brain-On-A-Roomba / Bud Askins Dallas Goldtooth as Charles Whiteknife Chris Parnell as Overseer Benjamin Angel Desai as Cassandra Hawthorne Eric Berryman as Lloyd Hawthorne Cherien Dabis as Birdie Matt Berry as Sebastian Leslie Glenn Fleshler as Sorrel Booker Co Starring Justice Hedenberg as The Ghoul Stunt Double Hannah Scott as Lucy MacLean Stunt Double Teagan Meredith as Janey Howard Logan Crawford as News Anchor Harry Sutton Jr. as Dr. "Nose" Edmundson Chip Carriere as Nurse Powell Mohammed J. Ali as Vault 4 Dweller Morgen McKynzie as Female Server Brandon McClary as Dr. "Nose" Edmundson Stunt Double Neimah Djourabchi as Vault 4 Dweller Elise Levin as Friendly Vault 4 Dweller #2 Dejay Roestenberg as Vault 4 Dweller Vick Krishna as Friendly Vault 4 Dweller #1 Christopher Parker as Sheriff Rex David Denowitz as Party Guest #2 Alex Purcell as Party Guest #3 Zeby Khan as Party Guest #1 Russell Ewing as Sheriff Troy Maria Del Mar González as Subject 476 Justin Carney as Vault 4 Dweller
