Guest Stars Frances Turner as Barb Howard Sarita Choudhury as Kate Williams / Lee Moldaver Michael Esper as Brain-On-A-Roomba / Bud Askins Dallas Goldtooth as Charles Whiteknife Chris Parnell as Overseer Benjamin Angel Desai as Cassandra Hawthorne Eric Berryman as Lloyd Hawthorne Cherien Dabis as Birdie Matt Berry as Sebastian Leslie Glenn Fleshler as Sorrel Booker Co Starring Justice Hedenberg as The Ghoul Stunt Double Hannah Scott as Lucy MacLean Stunt Double Teagan Meredith as Janey Howard Harry Sutton Jr. as Dr. "Nose" Edmundson Logan Crawford as News Anchor Brandon McClary as Dr. "Nose" Edmundson Stunt Double Neimah Djourabchi as Vault 4 Dweller Morgen McKynzie as Female Server Mohammed J. Ali as Vault 4 Dweller Zeby Khan as Party Guest #1 Russell Ewing as Sheriff Troy Elise Levin as Friendly Vault 4 Dweller #2 Vick Krishna as Friendly Vault 4 Dweller #1 Dejay Roestenberg as Vault 4 Dweller David Denowitz as Party Guest #2 Chip Carriere as Nurse Powell Alex Purcell as Party Guest #3 Christopher Parker as Sheriff Rex Maria Del Mar Gonzalez as Subject 476 Justin Carney as Vault 4 Dweller
