Antonio Raul Garcia
voices Oscar
Asher Bishop
voices Oscar
Oona Laurence
voices Hedgehog
Julia Pott
voices Susie
Indie Nameth
voices Lucy
Issac Ryan Brown
voices Max
Ramone Hamilton
voices Max
Sam Lavagnino
voices Pepper
Julian Edwards
voices Pepper
Nikki Castillo
voices Betsy
Charlyne Yi
voices Alice
Fortune Feimster
voices Ava
Naomi Hansen
voices Pajamas
Alexa Nisenson
voices Alexa
Bobby Moynihan
voices Jimjams
Bobby Moynihan
voices Mortimer
Lesley Nicol
voices Ramona
Andre Robinson
voices Oliver
Mike Birbiglia
voices Howard
Sam Lavagnino
voices King
Dylan Alvarado
voices King
Whoopi Goldberg
voices Barb
Kimiko Glenn
voices Margot
Cedric the Entertainer
voices Moon
Stefan Johnson
voices Moon
Alia Shawkat
voices Blanche
Ethan Maher
voices Puddle
Faye Larkin
voices Mildred
Mattea Quin
voices Lem
Mykal-Michelle Harris
voices Lem
Daphne Thomas
voices Lem
Kathleen Wilhoite
voices Sue
Bobby Moynihan
voices Melvin
Jo Firestone
voices Mallory
Alfred Molina
voices Andy
Aparna Nancherla
voices Opie
Elijah Wood
voices Saxophone
Stephen Root
voices Stuart
Richard Kind
voices Shark
Charlyne Yi
voices Nancy
Vanessa Lee Chester
voices Nancy
Caleb McLaughlin
voices Ghost the Boy
Xavier Patterson
voices Ghost the Boy
Melanie Lynskey
voices Sun
Doug Benson
voices Bassoon
Laraine Newman
voices Hedgehog's Mom
Paula Poundstone
voices Paulette
Max Mitchell
voices Prophecy Alien
Nikki Castillo
voices Sarah
Sarah Lloyd
voices Sarah
Jason Maybaum
voices Fife
Betsy Sodaro
voices Skadi
Kevin Michael Richardson
voices Waylon
Kate Berlant
voices Striped Horse
John Early
voices Bearded Sheep
Kent Osborne
voices Ghost Dad Kent
Cole Sanchez
voices Ghost Dad Cole
Bobby Moynihan
voices Toad Doctor
Julian Barratt
voices Poppawoppa
Shirley Henderson
voices Mum
Ashley Jensen
voices Miss Mary
Alex Lawther
voices Mildred's Friend
Aparna Nancherla
voices Agatha
Niki Hyun Yang
voices Heather D
Rylee Alazraqui
voices Alien
Isobel Chinnery
voices Ramona Age 8
Frances Conroy
voices Ms. Clarinet
Remi Edgerly
voices Noodle
Garret Davis
voices Toothpaste
Maria Bamford
voices Toothpaste
Fortune Feimster
voices Dolly
Lauren Lapkus
voices Olf
Kent Osborne
voices Chet
Maria Bamford
voices Sandy
Gaille Heidemann
voices Helen
Sally Struthers
voices Rose
Poppy DeAbaitua
voices Young Susie
Mia Lynn Bangunan
voices Kid Mouse 1
Fred Melamed
voices Receptionist Monk
Quinn Minichino Eakins
voices Moonbeam
Niki Hyun Yang
voices Rosie
Sunita Mani
voices Lucyola
Georgie Glen
voices Adult Mildred
Joanna Lumley
voices Adult Susie
Alia Shawkat
voices Butter Goth
Kate Flannery
voices Georgina
Kent Osborne
voices Alligator Chef
Cole Sanchez
voices Alligator Chef
Cole Sanchez
voices Freddie
Lorraine Bracco
voices Werewolf Queen
Richard Kind
voices Jim
Melissa Villaseñor
voices Psychic
Bella Ramsey
voices Ramona Age 15
Lesley Nicol
voices Emma
Cole Sanchez
voices Yeti Orderly
Audrey Wasilewski
voices Yeti Nurse
Kate Micucci
voices Accordion
Keith David
voices Lithophone
Bobby Moynihan
voices Dennis
Niki Hyun Yang
voices Shortcake
Max Mitchell
voices Patootie
Lucian Perez
voices Glazed Ham
Cole Sanchez
voices Salt Parasite
Frances Conroy
voices Lead Patrol Elf
Cole Sanchez
voices Alligator 1
Travis McElroy
voices Cutie
Bobby Moynihan
voices Old Log Ghost
Fred Stoller
voices Ghost the Earnest
Lorraine Toussaint
voices Emily Ghost
Richard Masur
voices The Broom Maker
Audrey Wasilewski
voices Red Haired Moom
Dee Bradley Baker
voices Stair Rabbit
Maria Bamford
voices Foghorn
Keith David
voices Tummy
Aimee Mann
voices Siren
Maria Bamford
voices The Royal Mush
Roz Ryan
voices The Death Cap
Max Mitchell
voices Jeremiah
Maria Bamford
voices Puffer Fish
Loretta Devine
voices Sea Cow
Cole Escola
voices Sea Slug
Elsie Fisher
voices Sea Snail
Scott Hoying
voices Blobfish
Eva Victor
voices Sea Susie
Wallace Shawn
voices Pete
Lolly Adefope
voices Snowflake
Danny Pudi
voices Cookiesmell
Maria Bamford
voices Polly
Fortune Feimster
voices Vern
Kevin Michael Richardson
voices Langston
Thomas Herpich
voices Carl
Keith Ferguson
voices Ghost Pendarvis
Jeremy Crutchley
voices Frog Musician
Alice Pott
voices New Susie
Chris Fleming
voices Professor Q
Jeremy Crutchley
voices Theo
Kate Dickie
voices Professor Elliot
Stephen Root
voices Prime Monister
Kimiko Glenn
voices Ski Bat
Cole Sanchez
voices Vann
Iris Bahr
voices Mother Mouse
Tony Curran
voices Ryan
Lauren Mei
voices Kid Mouse 2
Mathieu Szymkowiak
voices Papa Mouse
Bobby Moynihan
voices Peach Stand Guy
Julian Barratt
voices Sandwich Monk
LaTanya Richardson
voices Queen Bee
Yara Shahidi
voices Beanie
Niki Hyun Yang
voices Batilao
Momona Tamada
voices Bethie
Sacha Dhawan
voices Miracle Rabbit
Mia Lynn Bangunan
voices Baklava
Roz Ryan
voices Grandma Trumpet
Vanessa Lee Chester
voices Minituni
Kent Osborne
voices Grigory Midnight
Isla Ashworth
voices Young Mildred
Dylan Alvarado
voices Frog Prince
Alia Shawkat
voices Wereflower
Kevin Michael Richardson
voices Time
Justin Felbinger
voices Dungeon Doug
Bob Balaban
voices Gerald
Remi Edgerly
voices Mystical Alien
Luke Lowe
voices Basketball
Nat Faxon
voices Popular Banana Split
Ethan Maher
voices Boyband
Brenda Vaccaro
voices Godmonster
Brian Baumgartner
voices Storm Cloud
Bobcat Goldthwait
voices Monk Voice
Lori Petty
voices Ms. Pinch
Don Lake
voices Dr. Hogsbottom
Jane Lynch
voices Skadi's Mom
Cole Sanchez
voices Frog King
Niki Hyun Yang
voices Egg
Rachel Dratch
voices Bernadette
Carol Kane
voices Barb Jr.
Wanda Sykes
voices Ethel
John Hodgman
voices Bartholomole
Wallace Shawn
voices Morris Mole
Kathleen Turner
voices Mole Judge
Fortune Feimster
voices Mrs. Goose
Bobby Moynihan
voices Tub
Cooper Friedman
voices Caboodle
Ethan Maher
voices Dream Boy (Susie)
Wallace Shawn
voices Barry
Steve Berg
voices Harry
Aparna Nancherla
voices Oddjobs