Jonathan Ray Banks first notable film roles were in the films Airplane! (1980), 48 Hrs. (1982), and Beverly Hills Cop (1984). He has received critical acclaim for his role as former police officer turned hitman Mike Ehrmantraut in the television series Breaking Bad (2009–2012) and its spin-off Better Call Saul (2015–present) as well as El Camino: A Breaking Bad Movie. Earlier he was well-reviewed as Frank McPike in Wiseguy (1987–1990).
He has received six Primetime Emmy Award nominations for Outstanding Supporting Actor in a Drama Series (1989, 2013, 2015-2017, 2019) for his work on all three series, making him the only actor with nominations as a main cast member for three different shows in this category, two of which feature him as the same character.